Guangzhou Shifei Biotechnology Sterile Cleanroom and GMPC Renovation Project_Deiiang

▸ Planning Stage: Functional Layout & BIM Coordination

During the planning stage, we first aligned with the client's production capacity roadmap and product categories — including skincare products and functional cosmetics — while strictly referencing the Good Manufacturing Practice for Cosmetics (GMPC) and relevant cleanroom building standards. The overall functional layout was systematically organized, covering the raw & auxiliary material staging area, weighing room, batching room, emulsification room, filling room, primary/secondary packaging rooms, finished goods staging area, and quality inspection laboratory. Each zone was assigned a defined cleanliness classification, with clearly mapped material flow routes, personnel flow routes, and material transfer paths.

A key challenge stemmed from the constraints of the client's existing building — limited floor-to-ceiling height, load-bearing capacity, and existing structural conditions for water supply, electrical power, and exhaust ventilation. Through thorough on-site survey and structural review, we proposed an overarching strategy of "partial overhead mezzanine + zoned integrated utility pipeline layout". This approach preserved the main structure with minimal modifications while reserving space and connection points for future production expansion pipelines and equipment positions.

The most significant difficulty at this stage was the shortage of integrated pipeline space within the existing building — particularly the multi-discipline conflicts arising from overlapping HVAC air ducts, process pipelines (purified water, process cooling, steam), fire sprinkler systems, and cable trays. Our solution involved pre-emptive 3D comprehensive layout coordination within a BIM model. By applying elevation zoning, cable tray layering, and partial flattening design of air ducts, we simultaneously ensured adequate maintenance access clearance, met the required air volume and velocity specifications, and substantially reduced on-site design changes and rework during construction.

▸ Construction Stage: Schedule Management & Cleanroom Fit-Out

During the construction stage, the Deliang Project Department implemented a refined schedule management system and a demonstration-led (model-first) approach. The scope of works encompassed structural reinforcement, cleanroom envelope and partition systems, purification air conditioning engineering, process piping, water supply & drainage, electrical systems, and automatic control systems — all executed under strict quality oversight.

Regarding cleanroom interior finishing, the construction sequence strictly followed the "top-to-bottom, inside-to-outside" principle. All concealed works — including air duct insulation, pipeline thermal insulation, and support & hanger reinforcement — were documented with both photographic and written records, ensuring that the as-built documentation remains complete and fully traceable for future reference, audits, and maintenance purposes.

▸ HVAC Purification System & Electrical / Automation Control

In the HVAC purification system, particular attention was paid to air volume balance control, optimal positioning of supply and return air outlets, and precise air velocity regulation. Throughout the construction process, pressure gauges, temperature & humidity probes, and building automation control points were concurrently installed in穿插 (interleaved) fashion, reserving all necessary conditions for the subsequent system commissioning, testing, and validation phase.

In the electrical and automation control scope, cleanroom lighting, air handling units (AHUs), motorized dampers, electric doors, and related equipment were integrated into a centralized monitoring system. Additionally, pre-embedded conduits and reserved interfaces were put in place for future energy consumption tracking and sub-metering, enabling detailed operational cost analysis and energy efficiency optimization over the facility's lifecycle.