How to ensure the safety of clean rooms

The safety of modular clean rooms is the key to ensuring the quality of laboratory environment and the health of staff. Effective clean room safety management includes the safety of building structures, biosafety, circuit system safety and fire protection system safety. These aspects will be elaborated in detail below.

Clean room building structure safety

1. Structural material selection

The Building Materials of clean rooms should comply with international standards, such as ISO 14644. The use of stainless steel and fire-retardant coatings not only improves corrosion resistance, but also effectively prevents pollution and ensures the long-term safety of clean rooms.

2. Isolation and ventilation design

The Clean room design should include a good isolation and Ventilation system. An air change rate of at least 20 times per hour can ensure that the concentration of particulate matter is controlled at an extremely low level and reduce the risk of cross contamination.

3. Sealing test

The sealing of the building structure directly affects the efficiency of the clean room. By regularly conducting air tightness tests (such as using an air tightness tester), ensure that there is no air leakage and maintain the stability of the indoor environment.

Biosafety

1. Microbial control

The primary task of biosafety is to control microbial contamination. According to WHO guidance, microbial monitoring should be carried out regularly in clean rooms to ensure that the number of bacteria per cubic meter of air is less than 100.

2. Use of biosafety cabinets

When handling biological samples, biosafety cabinets that meet international standards (such as BS EN 12469) should be used. Such equipment can provide the necessary protection to prevent the spread of biological contamination.

3. Personal protective equipment (PPE)

Staff must wear appropriate personal protective equipment when handling biological samples. Studies have shown that appropriate PPE can reduce the risk of infection by more than 90% and protect the health of staff.

Circuit system safety

1. Standardization of electrical equipment

Electrical equipment in clean rooms should comply with IEC 60601 standards to ensure the safety and reliability of the equipment. This can effectively avoid safety hazards caused by electrical failures.

2. Anti-static measures

Anti-static measures should be taken in modular clean rooms, such as grounding the ground and equipment. According to the ANSI/ESD S20.20 standard, the damage rate of electrostatic discharge to Electronic products can be as high as 30%, so anti-static measures are particularly important.

3. Regular inspection and maintenance

The circuit system of the clean room needs to be inspected and maintained regularly. Electrical equipment should undergo a comprehensive safety assessment every year to ensure its normal operation and timely detection of potential hazards.

Fire protection system safety

1. Fire alarm system

The clean room should be equipped with a fire alarm system that complies with NFPA standards to ensure that it can quickly alarm in the event of a fire, reduce fire losses, and protect personnel safety.

2. Fire extinguishing equipment configuration

Based on the building area and risk assessment, the configuration of fire extinguishing equipment should comply with local fire regulations. Clean rooms should be equipped with at least 1 fire extinguisher per 100 square meters to deal with sudden fires.

3. Emergency evacuation plan

Develop a detailed emergency evacuation plan and conduct drills regularly. According to the NFPA 101 standard, all staff should be familiar with the evacuation route to ensure that they can evacuate quickly and safely in an emergency.

Ensuring the safety of clean rooms requires comprehensive consideration of building structure, biosafety, circuit system, fire protection system and other aspects. By following international standards, regular inspections and effective management measures, clean rooms can be operated safely and efficiently, providing a reliable environment for scientific research and production.