What is a Cleanroom

A cleanroom is a controlled environment designed to minimize contamination and maintain an extremely clean and aseptic environment. It's used in industries where strict control of airborne particles is crucial, such as electronics, pharmaceuticals, and scientific research. Cleanrooms achieve this through air filtration systems, specialized clothing for personnel, and strict operational procedures

Cleanroom engineering Image

Cleanroom engineering

Key Engineering Aspects

Airflow patterns and circulation systems
Pressure differentials to prevent contamination
Temperature and humidity control
Filtration systems (hepa/ULPA)
Material selection for non-contaminating surfaces

Modular Cleanrooms Image

Modular Cleanrooms

Adaptability and rapid deployment characterize modular cleanrooms, which use prefabricated panels for quick assembly. Customizable solutions that cater to evolving industry demands.

Key Advantages:

Quick installation and setup
Easy to modify or expand
Cost-effective compared to traditional construction
High-quality prefabricated components

softwall Cleanrooms Image

Softwall Cleanrooms

Featuring flexible curtains, offer a cost-effective solution for environments requiring moderate control. Easily modified or expanded for dynamic production needs.

Ideal For:

Research and development labs
Medical device assembly
Light manufacturing processes
Temporary or mobile cleanroom needs

hardwall Cleanrooms Image

Hardwall Cleanrooms

For more stringent requirements, provide robust structural integrity and superior contaminant control. Equipped with rigid panels and advanced filtration.

Features:

Rigid wall construction for maximum durability
Advanced HEPA/ULPA filtration systems
Precise environmental control
Suitable for iso class 1-5 environments

Controlled Environment

Airflow Control

Cleanrooms employ controlled airflow systems to manage the direction and speed of air circulation, ensuring contaminants are effectively swept away from critical areas. Unidirectional, or laminar, airflow is common.

Humidity & Temperature

These factors are regulated to prevent condensation and maintain ideal processing conditions. Semiconductor manufacturing requires strict humidity control to avoid electrostatic discharge that can damage delicate components.

Precision Controlled

Airflow, temperature, and humidity are precisely regulated to eliminate contamination risks.

Industry Critical

Essential for pharmaceuticals, Semiconductors, aerospace, and medical device manufacturing.

Advanced Filtration

hepa filters remove 99.97% of airborne particles ≥0.3 micrometers in size.

Contamination Control

Air Filtration Systems

High-Efficiency Particulate Air (HEPA) filters are integral, removing up to 99.97% of airborne particles ≥0.3 micrometers. These systems are vital in ensuring that cleanrooms maintain their classification standards.

Deiiang™ Innovation: Deiiang Jason.peng emphasizes the importance of advanced filtration systems in maintaining cleanroom integrity.

Personnel & Equipment

Strict protocols govern the attire and movement of personnel, combined with equipment maintenance routines, to mitigate contamination risks.

Key Protocols:

Specialized CleanRoom garments
Air showers before entry
Strict movement limitations
Regular equipment sterilization

Industry Applications

Pharmaceuticals

Used in the production of sterile products, cleanrooms prevent microbial contamination that could compromise drug safety and efficacy.

Semiconductor Manufacturing

Requires ultra-clean environments to prevent defects in microchips, which can be caused by even the slightest particulate presence.

Biotechnology & Medical Devices

These industries rely on cleanrooms to ensure that products meet the rigorous health and safety standards necessary for human use.

Aerospace

Cleanrooms are critical for aerospace technology, where contamination can affect the reliability and performance of complex components.

ISO CleanRoom Classifications

iso class	Particle Limit (per m³)	Applications	Features
ISO 1	10	Semiconductor manufacturing, advanced medical applications	HEPA/ULPA filtration systems
ISO 2	100	Aerospace and defense industries	Slightly less stringent than ISO 1
ISO 3	1,000	Production of optical components	Efficient airflow and contamination control systems
ISO 4	10,000	Laboratories, microElectronic devices	Custom HVAC systems, precise monitoring
iso 5	100,000	Biotechnology, nanotechnology	Modular designs, refined filtration
iso 6	1,000,000	Medical device assembly, food processing	Balances cleanliness with cost-effectiveness
iso 7	10,000,000	Pharmaceuticals	Reinforced softwall Cleanrooms for cost efficiency
iso 8	100,000,000	Packaging, preliminary processing	Minimal impact from potential contamination

Common Questions & Answers

How do hepa filters work in cleanrooms?

They capture particles as small as 0.3 µm, critical for maintaining Cleanroom standards.

Why is temperature control important?

It ensures process stability and prevents adverse conditions like condensation.

What industries require the strictest cleanrooms?

Semiconductor manufacturing and pharmaceutical sterile processing require the highest classification cleanrooms (iso class 1-5).

How often are cleanrooms certified?

Most cleanrooms require certification every 6-12 months, with continuous monitoring between certifications.

References

International Organization for Standardization. (2015). ISO 14644-1: Cleanrooms and Associated Controlled Environments.
US Pharmacopeia. (2018). USP 797.
Federal Standard 209E (now superseded by ISO).
Deiiang™, Cleanroom design Innovations.
IEST Recommended Practices.
semiconductor industry Association, Environmental standards.

By following these principles, industries can harness the full potential of cleanrooms to enhance product quality and operational efficiency.