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how decontamination is done clean room

  • Author:Jason Peng

  • Cleanroom Engineering Technology Manager of Deiiang Company.

    Product R&D Manager of GDC Inc. Cleanroom Equipment Manufacturing Company.

    Executive Director of Guangdong Cleanroom Industry Association of China.

    Engaged in R&D of related products for 15 years, with rich relevant technical experience

  • 2024-11-06  |  Visits:

Airflow Operation Mode

The airflow operation mode of a modular cleanroom is critical because it controls the movement and removal of particles. Laminar and turbulent flow are two common airflow modes:

Air Flow Pattern In Clean room|Tahir Hussain Mep Industry

  • Laminar flow:

    air flows in parallel laminar flow, minimizing turbulence and particle dispersion. Laminar flow cleanrooms are often used in applications with the most stringent particle control requirements, such as Semiconductor manufacturing and precision instrument assembly.

  • Turbulent flow:

    Air flows in an irregular and unpredictable manner, resulting in greater mixing and dilution of particles. Turbulent flow cleanrooms are often used in applications with lower particle control requirements or requiring high air exchange rates, such as pharmaceutical production and biotechnology research.

Pharmaceutical Cleanroom Design & ISO 14644-16 | Pharmaceutical Engineering

Air Filtration

High-efficiency Air Filters (hepa) and ultra-low penetration air filters (ULPA) are key components for cleanroom air purification.

  • HEPA filters:

    According to the EN 1822 standard, HEPA filters can remove more than 99.99% of particles of 0.3 microns.

  • ULPA Filters:

    According to ISO 29463, ULPA filters remove more than 99.999% of particles as small as 0.1 microns.

    HEPA and ULPA filters are often installed in the air supply system of A CleanRoom to remove airborne particles.

HEPA / High Efficiency Particulate Air Filter Consulting Service - Steve  Fontaine

Air Circulation

High air exchange rates are essential for diluting and removing airborne particles. The ISO 14644-1 standard recommends that the air exchange rate for ISO 8 Cleanrooms should be 20-30 times per hour. This means that the air in the cleanroom should be completely replaced 20-30 times per hour.

High air exchange rates can be achieved by:

  • Increasing the supply Air volume

  • Reducing the exhaust air volume

  • Using a recirculating air system

By implementing these purification methods, modular cleanrooms can maintain a high level of air cleanliness, providing a controlled and contamination-free environment for sensitive products and processes.

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