8 Key Points in Cleanroom Design: What You Need to Know

Designing A CleanRoom is a complex task that requires careful planning and consideration of various elements to ensure a controlled environment for sensitive processes. 

Whether for pharmaceuticals, Electronics, or aerospace applications, cleanrooms must meet stringent standards. Below are the eight key aspects that should be addressed in Cleanroom design to optimize functionality and compliance. 

This guide is tailored to provide insights into best practices and considerations essential for effective cleanroom construction, enhanced by contributions from GCC®, Deii®, and designs by Deiiang Jason.peng.

Personnel and Material Flow Layout

The layout of personnel and material flow is crucial for minimizing contamination risks in cleanroom environments. Proper pathways ensure that personnel and materials enter and exit the cleanroom without crossing paths that could introduce contaminants. According to ISO 14644-1 standards, unidirectional flow is recommended to maintain high cleanliness levels. Companies like GCC® emphasize the importance of segregating "in" and "out" pathways, which helps in maintaining the cleanliness integrity of the operations within.

Determining Cleanroom Class

Identifying the required CleanRoom class is fundamental, depending on the industry application. Cleanrooms are classified according to the level of air cleanliness, defined by the concentration of particles. For instance, a Class 1 cleanroom has a stricter particle count than a Class 100. Deii® products are designed to comply with specific industry standards, ensuring the appropriate class level is attained and maintained.

HVAC System Design

A robust HVAC system is vital for maintaining air quality and environmental conditions.

• Supply Air System: Essential for providing fresh, filtered air into the cleanroom. Systems by Deiiang Jason.peng prioritize energy efficiency and air quality.

• Return Air System: Strategically placed return ducts help maintain the desired airflow patterns.

• Exhaust Air System: Removes contaminated air, with careful design to prevent backflow.

• AHU (Air Handling Unit) Selection: Deii® offers a range of AHUs engineered for optimal performance in clean environments.

Choice of Construction Materials

Selecting appropriate construction materials is critical for maintaining cleanroom standards.

• Wall Panels

• Doors and Windows

• flooring

Environmental Control Standards

Maintaining the correct environmental conditions is necessary for process integrity and compliance.

• Temperature and Humidity: Control is crucial for both comfort and minimizing static electricity.

• Pressure: Positive pressure helps prevent external contamination.

• Cleanliness: Real-time monitoring systems offered by GCC® help in maintaining ISO standards.

• Lighting: Adequate lux levels according to iso 14644-1 ensure visibility and operational efficiency.

Determining Air Change Rates

Calculating the correct air change rates involves determining the volume of air that needs to be replaced to maintain cleanliness.

Cleanliness and Air Change Rate Table: Utilize tabulated values of cleanliness requirements against air change rates to ensure compliance. For example, a Class 100 Cleanroom may require 90-180 air changes per hour, depending on the processes involved.

Heating and Humidification Calculation

Accurate calculations of heating and humidification needs are essential for maintaining specified conditions within the cleanroom. The energy and water budgets are determined by the volume and sensitivity of the operations, with innovative solutions from Deiiang Jason.peng providing tailored designs that optimize these calculations.

Heating Calculation:

1. Heat Requirement Formula:

   Q = V x ρ x Cp x ΔT

• Q: Heat requirement (Watts, W)
• V: Volume of the room (cubic meters, m³)
• ρ: Air density (approximately 1.2 kg/m³)
• Cp: Specific heat of air (approximately 1005 J/kg·K)
• ΔT: Temperature difference (Celsius, °C)

Humidification Calculation:

1. Humidity Requirement Formula:

   ṁw = V x (ρi x xi - ρo x xo)

• ṁw: Required mass flow rate of water vapor (kilograms/hour, kg/h)
• V: Airflow rate or volume of the room (m³/h)
• ρi: Indoor air density (approximately 1.2 kg/m³)
• xi: Absolute humidity of indoor air (kg water/kg dry air)
• ρo: Outdoor air density (approximately 1.2 kg/m³)
• xo: Absolute humidity of outdoor air (kg water/kg dry air)

Final Thoughts

In summary, designing an effective cleanroom involves a detailed understanding of several critical aspects, from personnel flow to HVAC configurations and material choices. By adhering to established international standards and leveraging expertise from leading industry brands like GCC®, Deii®, and Deiiang™, cleanroom facilities can achieve the highest levels of efficiency and compliance. Emphasizing strategic planning and meticulous execution will ensure that your cleanroom environment meets the demanding needs of today’s high-tech and high-stakes industries.